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Pernicious anemia is a condition that occurs when the body can not absorb enough vitamin B12. Lost in this particular condition, the cells that have the stomach capacity, sufficient to produce a substance called intrinsic factor. Why is it important? Since intrinsic factor initially combine to form a B-12 B12-intrinsic factor complex, so it can absorb the digestive system.
We know that vitamin B12 plays, also called cobalamin, is an important role in many processes:It helps red blood cells, supports the function of nerve cells, and also helps build DNA. In case of malfunction of the body's immune system and starts attacking the cells of the stomach that make intrinsic factor that influenced the decrease in production of intrinsic factor strongly B12, for the worse.
Pernicious anemia is also known in medical circles as megaloblastic anemia. The term describes the megaloblastic large, immature red blood cells in people suffering from this disease, which can be seenmore frequently in people of northern European descent. Often, pernicious anemia and vitamin B12 deficiency terms are used interchangeably, but it is important to note that the pernicious anemia refers only to B12 deficiency, which occurs when the lack of intrinsic factor.
What are the symptoms of pernicious anemia?
Weakness, fatigue, numbness
Tingling in hands and feet
Difficulty walking
Decreased appetite
Weight Loss
Nausea
Soft, smoothLanguage
Diarrhea
Irritability
Increased heart rate
Why is it important to integrate B12?
Although abnormalities of red blood cells can return to normal with vitamin B12, which supplements are improved when too much time passes before the pernicious anemia is determined, neuropathy (nerve damage), which causes numbness and tingling may be permanent. Pernicious anemia usually a routine checkup and blood tests (CBC or blood cells) found in the doctor's office. Peoplemore likely to develop are the elderly, vegetarians who do not integrate B12, and pregnant women.
An important note is that children breastfed by vegetarian mothers can easily develop vitamin B12 deficiency by the age of 4 to 6 months, because their liver reserves - the normally abundant - are limited and can be rapidly depleted because of their rapid growth (which translates into a strong demand for B12). One last thing to remember is that folic acid supplementation should not be takenVitamin B12, folic acid can only happen in reality, because to alleviate the anemia but allow neurological (nerve) deficit, the progress or even accelerate. For this reason, B12 and folic acid must be added to both together.
