Sunday, June 20, 2010

Tamiflu - The Magic Bullet for influenza

Tamiflu is the recipe for avian influenza, but may be useful in certain situations. For example, if you) have been in close contact with someone who is contagious work of a profession at high risk (eg health professionals. For the current influenza season, is quite effective, however, if the same efficiency of H5N1 have not known. Some data suggest that current H5N1 dose is not sufficient and can promote resistance. There are stilla lack, and if a pandemic breaks out, as soon, almost certainly rationed.

Some staff are essential may be hired from a prophylactic dose. Its use is rather limited therapeutic, as it must be given soon after symptoms and even then is not a panacea, but it reduced the maximum reduces the duration and severity.

Roche recommended dose (75 mg / day for prophylaxis and 150 mg / day in divided doses for threatment) may be necessary for the H5N1 and Vietnamese, to be doubled seen the most cases, increasing the duration of treatment from five to seven days:

"The virus virus to replicate at higher levels than normal human being, so it can focus more on virus drug to take control at this level,''said Jennifer McKimm-Breschkin, a virologist at the Australian Commonwealth Science and Industrial Research Organisation (CSIRO) in Melbourne.

Uncertainty about the effectiveness of Tamiflu in human H5N1 are even greater for H3N8> Now the most common virus in dogs. canine influenza is clinically similar to kennel cough (even if the kennel cough vaccine is not to protect against the flu, of course). Has a mortality of about 5% percent. Little is known about the pharmacokinetics of the drug in dogs known for how long should be given or whether the use in domestic animals may promote viral resistance (even the canine of the subtype H5N1 is different, unless there was recombination between N8 N1 and this seemsunlikely).

"Some patients with H5N1 infection, treated with the theory of Tamiflu had been resistant viruses emerge during treatment, ie, that higher doses prevent Widerstand''McKimm-Breschkin said emerging economies.

So long as the drug of this virus work, doubling the recommended dosage in essential reductions of benefits available in half. It 's interesting to note that the available supply their way in veterinary practice and used forDogs.

The same veterinary drug buzz about its use against the influence of newly identified canine and against other diseases such as parvovirus. Vets offer their findings on their websites and exchange Tamiflu anecdotes on the Veterinary Information Network, a members only place for animal doctors.

Although the prevalence of canine influenza is not yet known, researchers at a university found an infection rate of 15 percent between 2000 symptomatic dogstested.

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